The term polygenic disease includes many completely different metabolic disorders that every one, if left untreated, end in abnormally high concentration of a sugar referred to as aldohexose within the blood. DM sort one results once the exocrine gland now not produces important amounts of the internal secretion hypoglycaemic agent, typically because of the reaction destruction of the insulin-producing beta cells of the exocrine gland. DM sort two, in distinction, is currently thought to result from reaction attacks on the exocrine gland and/or hypoglycaemic agent resistance. The exocrine gland of an individual with sort two polygenic disease is also manufacturing traditional or maybe abnormally giant amounts of hypoglycaemic agent. different types of DM, like the assorted types of maturity onset polygenic disease of the young, might represent some combination of scant hypoglycaemic agent production and hypoglycaemic agent resistance. some extent of hypoglycaemic agent resistance may additionally be gift in an exceedingly person with sort one polygenic disease.